Sunday, May 17, 2009

New and Hot: Video of HIV Transmission between T-Cells

Mar 27 2009
http://www.hivandhepatitis.com/recent/2009/032709_b.html
http://huserlab.ucdavis.edu/HIV-movies.html
http://www.sciencemag.org/cgi/content/abstract/323/5922/1743

Researchers at Mount Sinai School of Medicine and UC Davis have captured the transmission of HIV between two t-cells on video. The scientists created a molecular clone of infectious HIV that contains fluorescent jellyfish protein and recorded transmission using quantitative high-speed video microscopy (powerful optical microscopy?). The video shows that transmission takes minutes. "Most prior studies of HIV dissemination have focused on free roaming viruses, but this study shows us how direct T cell-to-T cell contact could in fact be the predominant mode of dissemination within the body," said Dr. Benjamin Chen, one of the scientists working on the study.

Link to the videos:
http://www.youtube.com/watch?v=F8wf0zpo6Rs
http://www.youtube.com/watch?v=jzPKiFToItA

Elaine C

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